The Challenge:
Discovery of novel therapeutics for rare diseases affecting muscle, bone or nervous tissues has often been limited by poor understanding of complex molecular pathogenesis and often with unclear genetic to phenotypic link.
The Goal:
We aim to establish model systems that will help us better understand mechanisms underlying genetic to phenotypic link, pathogenesis or evolution of rare diseases affecting muscle, bone or nervous tissues.
The Solution:
We are searching for innovative in vitro culture system using primary or iPSC-derived cells in matrices that can enable us to better understand disease pathology and to identify novel targets and pathways.
